I’m just going to lay it out there with the risk of being viewed as overly promotional: Nicotinamide Ribosome (otherwise known as Niagen) has produced some very positive, albeit early-stage, results as a potential cure for Alzheimer’s.
This is potentially huge news for CDXC, the Company that owns all the licenses behind Niagen production. As many as 1 in 10 Americans over the age of 65 suffers from Alzheimer’s dementia. According to the Alzheimer’s Association the number of sufferers is set to grow dramatically.
As the size and proportion of the U.S. population age 65 and older continue to increase, the number of Americans with Alzheimer’s or other dementias will grow. This number will escalate rapidly in coming years, as the population of Americans age 65 and older is projected to nearly double from 48 million to 88 million by 2050.
Due to the large number of sufferers from, and the expense associated with Alzheimer’s, there is a ton of research going into preventing and/or reversing the effects of Alzheimer’s. Laboratories like that run by Johan Auwerx at the esteemed École Polytechnique Fédérale de Lausanne have been focused on reducing the formations of amyloid plaques, growth of which are commonly associated with Alzheimer’s.
In a paper published on December 6th in Nature, Auwerx released results generated by administering Nicotinamide Riboside first to worms, then, more importantly, to mice. The results of this were quite eye-opening. The paper itself is only available with a subscription, however there is a great summation of Dr. Auwerx’ work published by MedicalXPress, titled Healthy Mitochondria Could Stop Alzheimer’s, which is well worth reading.
The results of the trials run by Dr. Auwerx have demonstrated that Niagen could be a possible cure for Alzheimer’s. According to the report, the mice trials showed not only a significant improvement in mitochondrial function and a reduction in the number of amyloid plaques, but more importantly scientists observed a “striking normalization of the cognitive function of the mice”. Basically, a reversal of the effects of Alzheimer’s.
How was this possible? According to the report, “We have shown that restoring mitochondrial health reduces plaque formation– but, above all, it also improves brain function, which is the ultimate objective of all Alzheimer’s researchers and patients…By targeting mitochondria, nicotinamide riboside and other molecules that stimulate their ‘defense and recycle’ systems could perhaps succeed where so many drugs, most of which aim to decrease amyloid plaque formation, have failed.”
According to Chromadex, Niagen has proven to “promote healthy mitochondrial function, which is an important component of human aging.” The science is still early stage, but there are many ongoing studies, like that being done by Dr. Auwerx.
When you have a supplement that is proven to “increase metabolism and energy production in every cell,” it seems likely there will be many benefits from it. Perhaps one of the biggest benefits will be seen by those suffering from Alzheimers? Only time will tell, but I’m betting with Chromadex on this one.
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